Applications · Solid dose
The fastest tablet route is the least forgiving. Specify accordingly.
Direct compression skips granulation — so flow and lubrication have nowhere to hide. Small variations in glidant and lubricant show up immediately as weight variation and tooling issues. The answer is tightly specified, consistent Excipients.
Request Samples & CoAThe problem
What goes wrong, and why
Without wet or dry granulation to build flow and bulk, direct-compression blends rely entirely on the flow of the powder and the performance of the glidant and lubricant. That makes Excipient consistency — surface area, particle size, bulk density — the difference between a stable run and constant adjustment.
The Excipients that solve it
Match the grade to the problem
Magnesium Stearate
Lubricant and anti-adherent; a high-surface-area grade lets you keep the level low, which matters more in DC. WLSPL-MS TAB.
Purified Talcum Powder
Glidant for die-fill uniformity and reduced weight variation.
WLSPL-MS SOL
Water-dispersible Magnesium Stearate where dissolution of a soluble drug must not be compromised.
How to specify
What to put in your spec sheet
- Prioritise flow — pair a well-flowing blend with a glidant (talc) and minimal, well-distributed lubricant.
- Keep lubricant low and consistent — specify surface area and PSD, and control blend time.
- For soluble actives, consider a water-dispersible Magnesium Stearate grade.
FAQs
Direct Compression — common questions
What Excipients are best for direct compression?
How do I reduce weight variation in DC?
Can I protect dissolution of a soluble drug?
Proof before promises
Send us your direct compression problem — we'll recommend a grade.
Request Samples & CoA, or talk to a technical specialist.